Hardware · Embedded · Signal Processing · Applied ML
Mahdi Jazini
Sensor systems engineer, from circuit to validated data.
Bioengineering PhD with industry experience building mixed-signal hardware, embedded acquisition, DSP/ML pipelines, and validation systems. My current domain is cardiovascular monitoring; the engineering transfers to any product where noisy sensors must become trustworthy decisions. Available for full-time roles in early 2027.
Strongest where hardware, sensing, and data meet.
My domain depth is health sensing. My engineering toolkit is broader: I can own the signal chain from sensor interface and acquisition through algorithms, test, and validation.
About
I build real-world sensor systems end to end — from analog front ends and embedded acquisition to signal processing, machine learning, and validation.
I'm a PhD candidate in Bioengineering at the University of Pittsburgh (Biosignals track), advised by Prof. Ramakrishna Mukkamala. Cardiovascular monitoring is my proving ground: custom hardware and algorithms validated against invasive references in multi-site surgical studies.
I came to Pitt after a Master's in Integrated Circuits from University of Tehran and a Bachelor's in Digital Electronics from Amirkabir University of Technology. Between degrees I spent three years at Tosan Co. leading 14-layer mixed-signal PCB design and microprocessor signal-processing chains — I came to research with a production mindset.
That combination makes me useful beyond one application area. I work best on products where sensors are noisy, hardware and software interact, calibration matters, and the team needs evidence — not just a convincing demo.
total data collected; 34 in CO validation study
MACSOS 2025 · Safar 2025 · Safar 2026 · PDA 2026
+ 1 preprint under review (2 first-author at Pitt)
Featured Work
Smart Cuff
An end-to-end non-invasive platform that turns an automatic arm cuff into a hospital-grade hemodynamic monitor — pneumatics, ECG, respiration, and pressure on one system. Intended use: intraoperative and ICU hemodynamic monitoring; an investigational device today, no FDA submission yet.
Smart Cuff integrates custom mixed-signal PCBs (pump/valve PID control, pressure, and ECG front-ends) with a PyQt6 clinical GUI for real-time acquisition, automated calibration, and data collection in multi-site surgical studies. My first-author work on cardiac output estimation from Smart Cuff data earned the Outstanding Abstract Award at MACSOS 2025 and is under review (medRxiv 2025).
For clinicians: A continuous, catheter-free trend signal you could trust to direct a fluid bolus or vasoactive titration is the goal — comparable in trending performance to invasive pulse-contour today (concordance 83% vs. its 81%), but without the arterial line. Not yet a replacement for thermodilution at the population level; an addition to the toolkit when an arterial catheter isn't appropriate.
Where it sits: noninvasive cardiac-output landscape includes NICOM (bioreactance), ClearSight / CNAP (continuous finger cuff), and intermittent oscillometric devices. Smart Cuff aims to combine the form-factor of a familiar arm cuff with the trending capability typically reserved for finger cuffs — a single device for both BP and CO, with no consumables.
24 liver transplant + 10 cardiac
the invasive gold standard
above the 80% clinical-acceptability threshold; invasive pulse contour: 81%
- Custom mixed-signal PCB
- Pneumatic PID control
- ECG · pressure AFE
- PyQt6 clinical GUI
- Piecewise-linear valve cal
- Multi-site surgical studies
Time-Series Signal Toolkit
MATLAB/Python pipelines for noisy sensor data: filtering, harmonic-SNR quality gating, event detection, envelope fitting, spectral analysis, and interpretable feature extraction.
Acquisition & Control Software
PyQt GUI running on Raspberry Pi 5 and Windows, integrating configurable sensor arrays, MCC128 and NI-DAQ acquisition, PWM control, synchronized imaging, calibration, and repeatable deployment.
Mixed-Signal Hardware & Signal Chains (2019 – 2022)
Led 14-layer DSP/IF PCB design (EMI/EMC, PDN, thermal budgeting) for an electrical-motorcycle control unit. Built automated characterization workflows and directed microprocessor signal-processing chains on Artix-7 and Kintex-7.
Engineering Range
Sensor Hardware
& Instrumentation
Mixed-signal PCBs up to 14 layers, sensor analog front ends, ADC/DAC selection, power integrity, EMI/EMC, calibration, bench characterization, and failure analysis.
Embedded Acquisition
& Control
MCU and FPGA signal chains, C/C++, Raspberry Pi, DAQ integration, serial protocols, real-time acquisition, pneumatic PID control, and cross-platform PyQt tools.
Signal Processing
& Applied ML
Time-series filtering, FFT and spectral methods, event detection, physics-informed feature extraction, quality scoring, estimation models, and interpretable validation.
Now
- medRxiv revision — addressing reviewer comments on the cardiac-output paper, then submitting to a journal.
- Sub-diastolic hold prototype — closed-loop pressure tracking under DBP, with PDA + recalibration. Safety layers come first.
- Real-time quality scorer — a single number per measurement, derived from harmonic SNR, motion, and arrhythmia detection. So we never silently report a bad reading.
- Toolbox — adding a Bland–Altman builder and a PPG quality scorer. Public, free, opinionated.
The physics behind the cuff: arterial blood volume.
An arm cuff doesn't measure pressure directly — it reads volume oscillations from the artery underneath, mapped through a sigmoidal volume–transmural-pressure curve. Drag the cuff pressure: invasive arterial pressure rolls in along the X-axis, gets mapped through the curve, and rolls out as volume on the Y-axis. The output is loudest when the cuff sits exactly at MAP.
- Who — Sensor-systems engineer and Bioengineering PhD (Dec 2026). I own the full stack: hardware → embedded acquisition → signal processing / ML → test and validation.
- Proof — Shipped 14-layer industry hardware, built cross-platform acquisition software, published signal-processing methods, and validated a complete sensing system in 34 surgical patients.
- Want — Hardware/embedded R&D, sensor systems, DSP/algorithms, applied time-series ML, test/validation automation, or medical-device/wearable roles.
- Logistics — Available early 2027 · Pittsburgh, open to relocation / hybrid / remote · F-1 OPT.
Open to Work
Target roles
- Hardware / Embedded R&D Engineermixed-signal PCB, MCU/FPGA, control, bring-up
- Sensor Systems / Instrumentation Engineersensor interfaces, DAQ, calibration, characterization
- DSP / Algorithm Engineertime-series, spectral analysis, feature extraction
- Applied ML Engineersensor data, quality scoring, interpretable estimation
- Test / Validation Automation EngineerPython/C#, instruments, repeatable evidence
- Medical Device / Wearable R&Dphysiology, clinical studies, safety-minded systems
What I bring
- System ownershipsensor board → acquisition → algorithms → user-facing tool
- Hardware depthup to 14-layer PCBs, FPGA pipelines, AFE, EMI/EMC, PDN
- Physics-grounded algorithmsmodels tied to how the sensor and system actually behave
- Validation disciplinebench tests, automated characterization, clinical references
- Cross-functional communicationhardware, software, data, clinicians, papers, and demos
Best-fit problems
I do my best work on real-world sensing products where signal quality matters — medical devices, wearables, instrumentation, industrial sensing, robotics/automation, or semiconductor/test systems.
Start a conversation → Download full CV (PDF)It's all just signals.
Chased a decaying sine wave off a SAW sensor in 2018. Chasing an oscillometric envelope off an arm cuff now. The physics is different — the tricks are the same. Watch one morph into the other:
CV & Background
Download PDF-
Apr 2026★ Professional Development Award19th Research SymposiumUniversity of Pittsburgh
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May 2026★ Top PrizeSafar Symposium 2026Dept. of Anesthesiology · University of Pittsburgh
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Sept 2025★ Outstanding Abstract AwardMACSOS ConferenceUniversity of Pittsburgh"Cardiac Output Monitoring via an Automatic Arm Cuff Device: Potential in Surgical Patients."
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May 2025★ Top Poster PrizeSafar SymposiumDept. of Anesthesiology · University of Pittsburgh"Smart Cuff for Multi-Parameter Hemodynamic Monitoring."
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Aug 2022 – Dec 2026Education · PhD CandidatePhD, Bioengineering (Biosignals)University of PittsburghJoint coursework at Carnegie Mellon: Intro to ML (10-601), ML in Healthcare (10-742), DSP (18-691), Biostatistics (42-685).
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2022 – PresentTeaching & MentorshipTA / Instructor · Undergraduate & Graduate coursesUniversity of Pittsburgh · Prior: University of TehranLab assistant and instructor for undergraduate and graduate-level courses; co-mentoring junior researchers on signal-processing pipelines and hardware bring-up.
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2019 – 2022Experience · IndustryDigital Electronics EngineerTosan Co.Electrical-motorcycle control unit: 14-layer DSP/IF PCB design; automated characterization workflows; microprocessor signal-processing chains on Artix-7 and Kintex-7.
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2016 – 2018EducationMS, Integrated CircuitsUniversity of Tehran
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2012 – 2016EducationBS, Digital ElectronicsAmirkabir University of Technology
Technical Skills
Not a formal QMS role — but I've worked adjacent to these standards on clinical studies and can speak the language from day one.
Publications
Preprints & under review
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1Jazini, M., Daher, H., Kumar, R., et al. · medRxiv 2025.10.09.25337689Key result: 34 surgical patients (24 liver transplant + 10 cardiac). Cuff-based cardiac output estimates hit r=0.60, 83% concordance vs thermodilution — comparable to invasive pulse-contour performance (r=0.62, 81%) with no catheter.


Peer-reviewed
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2Dhamotharan, V., Jazini, M., Kumar, R., et al. · Scientific Reports 15, 35095Key result: A variable-ratio method (driven by max oscillogram amplitude) reduced systolic/diastolic BP errors from 5.8 / 1.5 mmHg → 1.5 / 0.8 mmHg — a ~4× improvement in systolic accuracy, and a window into how real home monitors actually work.

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3Momin, Md. A., Jazini, M., et al. · Analysis & Sensing


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4A novel combination of neural networks and FFT for frequency estimation of SAW resonators' responsesJazini, M. M., Khoshakhlagh, M., & Masoumi, N. · 5th Iranian Conf. on Signal Processing and Intelligent Systems, IEEE


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5Jazini, M. M. & Masoumi, N. · IRSS · IEEE

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6Jazini, M. M., Khoshakhlagh, M., & Masoumi, N. · Iranian Conf. on Electrical Engineering, IEEE

Conference Presentations
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May 2026
Smart Cuff: cuff-based multi-parameter hemodynamic monitoring. [Poster — Top Prize] 2026 Safar Symposium · Dept. of Anesthesiology · University of Pittsburgh
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Apr 2026
Smart Cuff for multi-parameter hemodynamic monitoring. [Professional Development Award] 19th Research Symposium · University of Pittsburgh
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Nov 2025
Cardiac output monitoring via an automatic arm cuff device: Potential in surgical patients. [Poster] IEEE-EMBS International Conference on Body Sensor Networks · Los Angeles, CA
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Sept 2025
Cardiac output monitoring via an automatic arm cuff device. [Poster — Outstanding Abstract Award] MACSOS Conference · University of Pittsburgh
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May 2025
Smart Cuff for multi-parameter hemodynamic monitoring: An initial non-invasive approach to cardiac output trend estimation. [Poster — Top Poster Prize] 2025 Safar Symposium · University of Pittsburgh
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2024
Novel approach to improving oscillometric blood pressure measurement by incorporating air volume measurements. [Poster] IEEE-EMBS International Conference on Body Sensor Networks
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2023
Toward improving the reproducibility of Valsalva maneuver responses. IEEE-EMBS International Conference on Biomedical and Health Informatics · Pittsburgh, PA
Talks & Media
Where I’ve shown the work, given a poster, or sat on a panel.
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May 2026
Smart Cuff: cuff-based multi-parameter hemodynamic monitoring. Top Prize, Safar Symposium · Anesthesiology, PittSymposium
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Apr 2026
Smart Cuff for multi-parameter hemodynamic monitoring. Professional Development Award, 19th Research Symposium · University of PittsburghAward
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Nov 2025
Cardiac output monitoring via an automatic arm cuff device. Poster, IEEE-EMBS Body Sensor Networks · Los Angeles, CAConference
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Sept 2025
Outstanding Abstract Award talk — same title, MACSOS Conference · University of PittsburghAward talk
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May 2025
Smart Cuff for multi-parameter hemodynamic monitoring. Top Poster Prize, Safar Symposium · Anesthesiology, PittSymposium
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2024
Improving oscillometric BP via air-volume measurement. Poster, IEEE-EMBS BSNConference
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2023
Toward improving the reproducibility of Valsalva maneuver responses. IEEE-EMBS BHI · Pittsburgh, PAConference
FAQ
The questions I get asked most often by recruiters and collaborators — answered up front, so we can use our first call for the interesting stuff.
When are you available to start?
I will defend in late 2026 and am targeting a January – March 2027 start date. For the right role I can consider a part-time or research-collaboration engagement earlier while I wrap up.
Remote, hybrid, or on-site?
All three work. I'm based in Pittsburgh but open to relocating anywhere in the U.S. For a strong team and problem fit, I'll also consider opportunities in Canada or Europe.
What kind of team fits you best?
I do my best work on cross-disciplinary R&D teams building real-world sensing products. The industry can vary; the common thread is hardware, embedded acquisition, algorithms, and rigorous validation working as one system.
Have you worked on regulated medical devices?
My clinical studies are IRB-approved and follow human-subjects research protocols. I haven't led a formal 510(k) or IDE submission, but I've worked adjacent to design controls, IEC 62304 software lifecycle, and ISO 14971 risk management — and I can speak the language from day one.
Can you code, or just design hardware?
Both — honestly, I'm an embedded systems engineer at heart, so I code and design electronics together; which side leads depends on the project. I ship the whole stack: custom PCB → firmware → signal processing → ML → clinical GUI. Python daily (Pandas/SciPy/PyTorch/PyQt), C/C++ for embedded, MATLAB for quick prototyping, Git for everything.
References?
Available on request — my PhD advisor and clinical collaborators (PIs and Co-PIs). Reach out by email and I'll share contact details.
How should I reach you?
Email is fastest: Mahdi.Jazini@pitt.edu. LinkedIn DMs work too. I reply within a day or two.
Let's talk
Hiring for hardware/embedded R&D, sensor systems, DSP/ML, or test and validation?
I'm open to roles across medical devices, wearables, instrumentation, industrial sensing, robotics/automation, and other data-rich hardware products. Based in Pittsburgh, PA — open to relocation, hybrid, or remote.